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Related Experiment Video

Updated: May 26, 2025

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits
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Emerging frontiers in sorghum genetic engineering.

Deepti Nigam1, Vikas Devkar1, Pallavi Dhiman1

  • 1Department of Plant and Soil Science, Institute of Genomics for Crop Abiotic Stress Tolerance (IGCAST), Texas Tech University, Lubbock, Texas, 79409, USA.

The Plant Journal : for Cell and Molecular Biology
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Summary

Genetically engineered sorghum offers solutions for food security, enhancing traits like stress tolerance and yield. Overcoming challenges in genetic modification is key to unlocking its full potential for global agriculture.

Keywords:
CRISPR/Cas9genetic engineeringgenetically modified organismgenome‐wide association studymorphogene‐assisted transformationprecision genome editingquantitative trait locisorghumtissue culturetransformation

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Area of Science:

  • Agricultural Science
  • Plant Biotechnology
  • Genetics

Background:

  • Sorghum is a vital climate-resilient cereal for food and feed in arid regions, facing challenges in yield, stress resistance, and grain quality.
  • Global population growth and climate change necessitate advancements in sorghum production.
  • Genetic engineering offers a pathway to improve desirable traits in sorghum.

Purpose of the Study:

  • To review the current status of genomic resources and genetic diversity in sorghum.
  • To highlight advancements and challenges in sorghum genetic engineering.
  • To discuss strategies for overcoming genetic engineering barriers and explore biosafety considerations.

Main Methods:

  • Review of existing literature on sorghum genomics, genetic diversity, and genetic engineering.
  • Analysis of advancements in genome editing technologies like CRISPR/Cas systems.
  • Exploration of strategies to improve transformation and regeneration efficiency.

Main Results:

  • Genome editing has improved sorghum's stress tolerance, nutrient use efficiency, and grain quality.
  • Significant obstacles remain, including low regeneration rates and genotype dependency.
  • Morphogenic regulators and optimized tissue culture techniques show promise for improving efficiency.

Conclusions:

  • Genetically engineered sorghum holds significant potential for addressing global food security.
  • Continued innovation in genetic engineering protocols and biosafety assessments is crucial.
  • Overcoming technical barriers is essential for the widespread application of improved sorghum varieties.