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Updated: May 26, 2025

An R-Based Landscape Validation of a Competing Risk Model
Published on: September 16, 2022
Intracluster correlation coefficients from cluster randomized trials conducted within the NCI Community Oncology
Anna C Snavely1, Heather J Gunn2, Ju-Whei Lee3
1Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC 27103, United States.
Abstract:
The intracluster correlation coefficient (ICC) measures the correlation of observations within clusters and is a key parameter for power and sample size calculations for cluster randomized trials (CRTs). To facilitate the design of future CRTs within the National Cancer Institute Community Oncology Research Program (NCORP), all studies from the NCORP website were reviewed to identify completed CRTs. ICCs for primary and secondary outcomes (when available) were ascertained from these trials and summarized in this article as a resource for future trial development. Although ICCs are relatively small for many outcome cluster combinations, that is not always the case, so consideration should always be given to the specific outcome of interest, trial design, and type of cluster when estimating an ICC to facilitate trial development.
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