Related Experiment Video
Updated: May 26, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Pigmentary demarcation lines: Three cases encapsulating a benign condition
Natalia Chalupczak1, Alexander Woods2, Allison Kirchner2
1Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
Abstract:
Pigmentary demarcation lines (PDL), or Voigt-Futcher lines, are lines marking an abrupt transition between hyperpigmented skin and normal skin. They are usually seen in African, Hispanic, and Japanese populations, but can be rarely observed in Caucasians. The distribution of these markings is postulated to follow "Voigt's lines," which mark the underlying peripheral nerves. We report three cases of patients presenting with PDL and review this phenomenon to raise awareness across specialties of this benign condition.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Pigmentation
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...

