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Updated: May 26, 2025

Bioluminescent Bacterial Imaging In Vivo
Published on: November 4, 2012
Bi2W2O9 Nanoflakes Synthesized via a Hydrothermal Method: Antibacterial Potency and Cytotoxicity Evaluation on Human
Muthamizh Selvamani1, Dilipan Elangovan1, Ali Alsalme2
1Department of Physiology, Saveetha Dental College & Hospitals, Saveetha Institute of Medical & Technical Sciences, Saveetha University, Chennai 600077, Tamil Nadu, India.
Abstract:
The prevalence of disease and death caused by pathogenic microbes is on the rise, and increasing rates of antibiotic resistance are concerning. This study investigates the antibacterial properties and cell viability (NHDF) behavior of synthesized Bi2W2O9 nanoflakes. The Bi2W2O9 nanoflakes were synthesized using the hydrothermal method, and their physical and compositional stability was analyzed through various characterization techniques, including X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared (FTIR), Raman, and DRS-UV. The Bi2W2O9 nanoflakes demonstrated promising antibacterial properties, with no significant cytotoxic effects, such as cell death or detachment, observed. This study confirms that Bi2W2O9 nanoflakes exhibit antibacterial activity against oral pathogens while maintaining 90% cell viability in normal human dermal fibroblast cell lines, paving the way for new therapeutic options for the treatment of oral infections.
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