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Related Concept Videos

Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

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Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
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Pneumonia I: Introduction01:30

Pneumonia I: Introduction

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Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
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Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
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Related Experiment Video

Updated: May 26, 2025

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
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Emphysematous osteomyelitis: A rare case report.

Siddartha Guru1, Navami Guru2, Rezhan Hussein1

  • 1Infectious Disease, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA.

Idcases
|February 24, 2025
PubMed
Summary

Emphysematous osteomyelitis, a rare bone infection with intraosseous gas, was diagnosed in a patient with metastatic colon cancer. The infection was caused by Clostridium septicum, a gas-forming bacterium.

Keywords:
Case reportClostridium septicumEmphysematous osteomyelitisInfection

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Area of Science:

  • Infectious Diseases
  • Oncology
  • Radiology

Background:

  • Emphysematous osteomyelitis is a rare condition characterized by gas within bone.
  • Gas-forming bacteria are typically implicated in its pathogenesis.

Observation:

  • A 63-year-old woman presented with back pain, appetite loss, and weight loss.
  • Imaging revealed a lytic lesion with gas in the T12 vertebral body.

Findings:

  • Bone cultures identified *Clostridium septicum*, a gas-forming anaerobic bacterium.
  • Cerebrospinal fluid studies were abnormal, raising concern for meningitis, though no bacteria grew.

Implications:

  • This case highlights the association between emphysematous osteomyelitis and underlying malignancy.
  • Successful treatment involved antibiotics and chemotherapy, underscoring a multidisciplinary approach.