getENRICH: a tool for the gene and pathway enrichment analysis of non-model organisms

The Gene Ontology system facilitates the functional annotation of genes by categorizing them into specific biological processes, cellular components, and molecular functions. Despite numerous tools like DAVID and Enrichr, analysing non-model organisms remains challenging due to a lack of genetic information and available tools.

To address this, we present getENRICH, a comprehensive tool for gene enrichment analysis tailored for non-model organisms. Available in both command-line and web-based graphical user interface (GUI) formats, getENRICH facilitates user-friendly interaction for gene dataset uploads, parameter configuration, and visualization. getENRICH employs hypergeometric distribution for P-value calculation and Benjamini-Hochberg correction for multiple testing.

getENRICH is freely available under the MIT license, with the source code, documentation, and example datasets available on GitHub (https://github.com/jnarayan81/getENRICH) and the GUI version available at https://getenrich.igib.res.in/.