Myocardial Infarction Caused by Aortic Root Thrombus in a Patient With Antiphospholipid Syndrome

Kazuki Ichihara1, Masataka Suzuki1, Hiromi Hashimura2

  • 1Department of Cardiology Kobe City Nishi-Kobe Medical Center Kobe Japan.

Clinical Case Reports
|February 24, 2025
PubMed

Insights

Aortic root thrombosis, a complication of antiphospholipid syndrome, can cause myocardial infarction. Cardiac imaging is crucial for diagnosing these conditions.

Area of Science:

  • Cardiology
  • Radiology
  • Rheumatology

Background:

  • Antiphospholipid syndrome (APS) is an autoimmune disorder associated with an increased risk of thrombosis.
  • Aortic root thrombosis is a rare but severe manifestation of APS.
  • Thrombosis in the aortic root can lead to serious cardiovascular events, including myocardial infarction.

Purpose of the Study:

  • To highlight the association between antiphospholipid syndrome and aortic root thrombosis.
  • To emphasize the diagnostic role of cardiac imaging in evaluating myocardial infarction and aortic root thrombosis in APS patients.

Main Methods:

  • Review of relevant literature and case studies.
  • Discussion of the diagnostic capabilities of cardiac computed tomography (CCT) and cardiac magnetic resonance imaging (CMR).

Main Results:

  • Aortic root thrombosis is an uncommon but critical complication of APS.
  • Myocardial infarction can be a consequence of aortic root thrombosis in APS.
  • CCT and CMR provide essential noninvasive methods for assessing both myocardial infarction and aortic root thrombosis.

Conclusions:

  • Early recognition and diagnosis of aortic root thrombosis in APS are vital.
  • Cardiac imaging techniques like CCT and CMR are indispensable for the accurate evaluation of APS-related cardiovascular complications.
  • Prompt diagnosis facilitates timely management to prevent severe outcomes such as myocardial infarction.