Addressing functional constipation in children: A call for comprehensive and collaborative management

Functional constipation (FC) is the most common gastrointestinal disorder in children, with a global prevalence of 14.4% based on Rome IV criteria. This editorial explores the multifactorial pathogenesis and diagnostic complexity of FC, emphasizing the importance of early and accurate diagnosis. Effective management of FC hinges on child-oriented toilet training and the use of osmotic laxatives, particularly polyethylene glycol. Emerging therapies, including probiotics, serotonin 5-HT4 receptor agonists, chloride channel activators, and herbal remedies, offer promising options but require further research. Lifestyle modifications, such as adequate fiber and fluid intake and physiotherapy, are crucial in supporting pharmacological treatments. For intractable cases, a multidisciplinary approach involving pediatric specialists, nutritionists, physiotherapists, and psychologists is essential. This comprehensive strategy aims to improve the quality of life for children with FC and their families through continuous research, education, and collaborative care.