Aperistalsis of the vas deferens corrected with administration of ephedrine

An infertile patient with azoospermia, normal spermatogenesis on a testis biopsy and no sperm seen on a post-ejaculate urinalysis underwent bilateral scrotal exploration. Normal anatomy was found at exploration and bilateral vasograms demonstrated the absence of obstruction. After subsequent therapy with ephedrine semen analysis showed a total sperm count of 72 million.