99m Tc-PSMA Scintigraphy of Subcutaneous Angiolipoma

We present a case of a 69-year-old man diagnosed with prostate adenocarcinoma, who underwent 99m Tc-PSMA scintigraphy as part of his initial staging workup. The scan revealed a focal uptake in the posterior abdominal wall, corresponding to a subcutaneous soft tissue lesion. Further evaluation using SPECT/CT imaging localized the lesion, which was subsequently excised and histopathologically diagnosed as an angiolipoma. This case represents the first reported instance of PSMA-based detection of angiolipoma as a false-positive finding using 99m Tc-PSMA scintigraphy.