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Isolated Atrial Amyloidosis in a Patient with Aortic Regurgitation and Paroxysmal Atrial Fibrillation
Hiroaki Kawano1, Nozomi Ueki2, Akira Senoo3
1Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Abstract:
A 65-year-old woman was admitted to our hospital with heart failure secondary to aortic regurgitation and paroxysmal atrial fibrillation (AF). During surgery for valve-sparing aortic root replacement, a biopsy was obtained from the right atrium because of paroxysmal AF and mild left ventricular hypokinesis. A histopathological examination revealed atrial natriuretic peptide amyloidosis, and the patient was clinically diagnosed with isolated atrial amyloidosis (IAA). Although IAA is rarely diagnosed clinically, it should be considered in patients with AF and heart failure.
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