A Comparative Analysis of Optical Biosensors for Rapid Detection of SARS-CoV-2 and Influenza

Airborne pathogens, such as influenza and SARS-CoV-2, pose significant health risks. While traditional diagnostic methods have limitations, optical biosensors offer a promising solution due to their rapid, sensitive, and cost-effective nature. This review focuses on the application of optical biosensors, including colorimetry, surface plasmon resonance, surface-enhanced Raman spectroscopy, and fluorescence techniques, for the detection of influenza and SARS-CoV-2. We discuss the advantages of these techniques, such as their potential for point-of-care testing and early disease detection. By addressing the limitations of existing methods and exploring emerging technologies, optical biosensors can play a crucial role in combating the spread of airborne pathogens. This review provides a comprehensive overview of optical biosensor techniques for the detection of both SARS-CoV-2 and influenza, addressing a significant gap in the literature.