Related Experiment Video
Updated: May 26, 2025
07:13
Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
4.2K
High Medication Non-Adherence Rates and its Drivers in the General Population: A Cross-sectional Study Using the
Rønnaug Eline Larsen1, Ala Karimi1, Tonje Krogstad1
1Deparment of Pharmacy, Faculty of Health Sciences, Oslo Metropolitan University, Oslo, Norway.
Summary
Many patients struggle with medication adherence due to forgetfulness or perceived health improvements. This study highlights the need for personalized interventions to improve medication outcomes.
Area of Science:
- Health Sciences
- Pharmacy Practice
- Behavioral Medicine
Background:
- Medication adherence is crucial for optimal health outcomes, yet significant variability exists among patients.
- Understanding medication-taking behaviors, barriers, and beliefs is essential for developing effective adherence interventions.
Purpose of the Study:
- To assess medication non-adherence and its causes in the general population using the OsloMet Adherence-to-medication Survey tool (OMAS-37).
- To compare adherence levels and non-adherence causes across different patient subgroups (cardiovascular, pain, mental health).
Main Methods:
- A cross-sectional study involving 812 medication users in Norway.
- Utilized the OMAS-37 tool to quantify adherence and identify 37 unique causes of non-adherence.
- Kruskal-Wallis tests were used for statistical comparisons between general population and patient subgroups.
Main Results:
- 64% of participants exhibited high non-adherence scores.
- Top reasons for non-adherence included forgetfulness (42%), perceived health improvement (40%), and fear of adverse drug reactions (39%).
- Positive adherence factors included older age, higher education, shared decision-making, and pill organizer use. Cardiovascular patients showed better adherence than pain and mental health subgroups.
Conclusions:
- The OMAS-37 tool revealed high rates of medication non-adherence and diverse causes across patient groups.
- Findings underscore the necessity for targeted, individualized adherence interventions to improve medication outcomes.
Keywords:
Medication adherenceOMAS-37cross-sectional studiesmedication safetynon adherencepatient-reported outcome measureshared decision makingMore Related Videos
Related Concept Videos
01:28Drug Therapy
34
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
34
01:25Factors Influencing Drug Absorption: Disease States and Pharmacology
405
Multiple disease states can significantly influence the oral drug absorption process by affecting blood flow and the functionality of the gastrointestinal (GI) system. Various GI diseases, including conditions that alter GI motility, such as diarrhea, decreased acid secretions (achlorhydria), and infections, have been associated with reduced drug absorption.
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
405
01:02Prescription, Nonprescription and Orphan Drugs
679
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
679
01:15Drug Abuse and Addiction: Pharmacological Phenomena
427
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
427
01:21Factors Affecting Drug Response: Overview
1.8K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
1.8K
01:17Drug Dependence
966
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
966