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Bibliometric insight into neoadjuvant immunotherapy in non-small cell lung cancer: trends, collaborations, and future

Pengliang Xu¹, Huanming Yu¹, Hupo Bian²

¹Department of Thoracic Surgery, The First People's Hospital of Huzhou, Huzhou, China.

Frontiers in Immunology

|February 25, 2025

Abstract

Background:

Neoadjuvant immunotherapy (NIT) is a rapidly emerging paradigm for advanced resectable non-small cell lung cancer (NSCLC). However, there is no bibliometric analysis in this research field.

Objective:

To analyze the hotspots and trends in the research of NIT for NSCLC and provide a reference for the study of NIT for lung cancer in China.

Methods:

Retrieve literature related to NIT for NSCLC from Web of Science, PubMed, and Scopus databases up to September 10, 2024. Use CiteSpace and VOSviewer software visualization software to analyze the keywords of country, author, institution, and literature.

Results:

There were 1575 references, and the overall annual publication volume showed an upward trend; Forde and Patrick M have published the most articles in the literature. The research hotspots mainly focus on chemotherapy, NIT for NSCLC, immunotherapy, neoadjuvant chemotherapy, pathological reactions, etc.

Conclusions:

This is the first bibliometric study comprehensively summarizing NIT's research trends and development in NSCLC. Our bibliometric assessment provides a panoramic view of the research milieu surrounding NIT for NSCLC, encapsulating the present state, evolving trends, and potential future directions, particularly emphasizing the promise of immunochemotherapy.

Keywords:

CiteSpace chemotherapy neoadjuvant immunotherapy non-small cell lung cancer visual analysis

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