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Carcinoid Heart Disease: A Classic One, But Not Always Remembered
Pamela Ramírez-Rangel1, Jorge D Rodríguez-Esparza2, Xochitl A Ortiz-Leon2
1Adult Cardiology Department, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, MEX.
Cureus
|February 25, 2025
Summary
A rare case of carcinoid heart disease (CHD) was diagnosed in a young woman initially presumed to have systemic lupus erythematosus. Advanced imaging revealed neuroendocrine tumors metastasized to the liver, causing severe heart valve dysfunction.
Area of Science:
- Cardiology
- Oncology
- Endocrinology
Background:
- Systemic lupus erythematosus (SLE) can present with diverse dermatological manifestations.
- Neuroendocrine tumors (NETs) can metastasize and lead to specific cardiac complications.
Observation:
- A 24-year-old female with presumed SLE developed right heart failure symptoms.
- Echocardiography revealed thickened, regurgitant tricuspid and pulmonary valves.
- Advanced imaging (CT, PET/CT) identified liver lesions consistent with metastasis.
Findings:
- Liver biopsy confirmed a well-differentiated neuroendocrine tumor.
- The patient was diagnosed with carcinoid heart disease (CHD).
- Multimodal imaging was crucial for diagnosing metastatic NETs and CHD.
Implications:
- This case highlights the importance of considering rare diagnoses like CHD in patients with unexplained heart failure.
- Early diagnosis and multimodal imaging are critical for managing carcinoid heart disease.
- Treatment involved somatostatin analog therapy and valve replacement surgery.
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