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Disseminated intravascular coagulation: a review of its pathogenesis, manifestations and treatment

D J Moore

    Journal of the South African Veterinary Association
    |December 1, 1979
    PubMed

    Disseminated intravascular coagulation is a clinicopathologic process of man and animals which occurs secondary to many diseases. The process may manifest in a variety of clinical syndromes including medical shock, haemorrhage, haemolysis and organ failure. A diagnosis can be confirmed by detecting a deficiency of several haemostatic components and the presence of raised levels of circulating fibrinogen (fibrin) degradation products. Therapy of the disorder includes the removal of the initiating factors which have provoked the clotting process together with the use of anticoagulants. The disease processes in which disseminated intravascular coagulation is implicated in the dog are enumerated.

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