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Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

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Published on: August 22, 2014

Magnetic-Plasmonic Core-Shell Nanoparticles: Properties, Synthesis and Applications for Cancer Detection and

Alberto Luis Rodriguez-Nieves¹, Suprava Shah¹, Mitchell L Taylor¹

¹Department of Chemistry, The University of Memphis, Memphis, TN 38152, USA.

Nanomaterials (Basel, Switzerland)

|February 25, 2025

Summary

Magnetic-plasmonic core-shell nanoparticles (MPNPs) offer combined magnetic and optical properties for advanced cancer theranostics. This review explores their synthesis, properties, and applications in multimodal cancer diagnosis and therapy, highlighting future clinical potential.

Keywords:

cancer detection cancer treatment core–shell magnetic property magnetic–plasmonic nanoparticles optical property

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Published on: May 22, 2020

Area of Science:

Biomedical Engineering
Materials Science
Nanotechnology

Background:

Nanoparticles are crucial in cancer research, with magnetic nanoparticles used for imaging and plasmonic nanoparticles for photothermal therapy.
Magnetic-plasmonic core-shell nanoparticles (MPNPs) integrate magnetic and optical properties, offering synergistic advantages.
MPNPs serve as a multimodal platform for cancer theranostics, including imaging, drug delivery, and photothermal ablation.

Purpose of the Study:

To review the properties and synthesis methods of magnetic-plasmonic core-shell nanoparticles (MPNPs).
To discuss the diverse applications of MPNPs in cancer diagnosis and treatment.
To examine the challenges and future perspectives of MPNPs in clinical settings.

Main Methods:

Literature review of magnetic-plasmonic core-shell nanoparticles.
Analysis of synthesis approaches and material properties.
Evaluation of applications in cancer imaging, drug delivery, and photothermal therapy.

Main Results:

MPNPs exhibit combined magnetic and optical functionalities for enhanced theranostic capabilities.
Synthesis strategies focus on core-shell architectures to optimize magnetic and plasmonic performance.
Applications demonstrate MPNPs' potential as contrast agents, drug carriers, and therapeutic agents.

Conclusions:

MPNPs represent a promising multimodal platform for integrated cancer diagnosis and therapy.
Further research is needed to overcome challenges for successful clinical translation.
MPNPs hold significant potential for advancing personalized cancer treatment strategies.