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Updated: Apr 6, 2026
Production of Metal Nanoparticles by Pulsed Laser-ablation in Liquids: A Tool for Studying the Antibacterial Properties of Nanoparticles
Published on: June 2, 2017
Surface Mesoscopic Characterization and Analysis of Nanosecond-Laser-Processed Molybdenum for the Optimization of
Jie Wang1,2, Qingyu Si1, Jia Lv3
1Shaanxi Engineering Research Center of Advanced Nuclear Energy, Shaanxi Key Laboratory of Advanced Nuclear Energy and Technology, School of Nuclear Science and Technology, School of Energy and Power Engineering, Xi'an Jiaotong University, Xi'an 710049, China.
Abstract:
Molybdenum has gained attention as a promising biomedical material due to its excellent mechanical properties and inherent antimicrobial activity. However, challenges remain in developing facile fabrication methods and further enhancing its antimicrobial efficacy. This study pioneers the investigation of biofilm inhibition by laser-treated molybdenum sheets against Pseudomonas aeruginosa (ATCC27853) and Staphylococcus aureus (ATCC25923). The experimental results demonstrate that nanosecond-pulsed laser processing significantly suppresses biofilm formation, reducing the minimum optical density (OD) values by 25.3% and 64.9% for the two bacterial strains, respectively. The laser treatment modifies the surface morphology of molybdenum by eliminating defects, reducing the effective contact area, and lowering hydrophobicity. Additionally, localized laser heating induces the formation of MoO3 on the surface, which reacts with water to generate molybdic acid-a key contributor to antibacterial activity. These findings highlight nanosecond-pulsed laser processing as a cost-effective, scalable surface-modification strategy for medical-grade molybdenum. This approach holds significant potential for broadening the antimicrobial applications of molybdenum-based biomedical devices and implants.
