Myocardial infarction with nonobstructive coronary arteries: A clinical review
1Jonathan Barnes is an adjunct professor in the PA program at California Baptist University in Riverside, Calif., and a PA fellow in advanced heart failure and transplant medicine at Mayo Clinic, Ariz. The author has disclosed no potential conflicts of interest, financial or otherwise.
Abstract:
Myocardial infarction with nonobstructive coronary arteries (MINOCA) is an important, often underrecognized working diagnosis. MINOCA is defined as an acute MI in a patient whose coronary angiography reveals no significant obstructive coronary artery disease. A comprehensive diagnostic approach beyond the initial coronary angiogram is essential for identifying this heterogeneous infarction pathophysiology. Distinguishing disease-specific causes affects patient management and prognosis, especially in female patients. This article provides an evidence-based overview of the tailored management strategies and ongoing clinical research likely to shape future guidelines.
