Related Experiment Video
Updated: May 26, 2025
Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
Published on: January 21, 2020
Assessing the Relationship Between Chronic Pain and Cognition: A NIDILRR and VA TBI Model Systems Collaborative
Mackenzie Peckham1, Cynthia L Beaulieu, Kaitlin Hays
1Author Affiliations: Craig Hospital Research Department, Englewood, Colorado (Ms Peckham, Dr Hays, Ms Lundstern, Ms MacIntyre, Dr Osborne, Dr Service, Mr Sevigny, Ms Welch, and Dr Tefertiller); Department of Physical Medicine and Rehabilitation, The Ohio State University College of Medicine, Columbus, Ohio (Dr Beaulieu); Department of Physical Medicine and Rehabilitation, Moss Rehabilitation Research Institute, Elkins Park, Pennsylvania (Dr Rabinowitz); and Department of Physical Medicine and Rehabilitation, School of Medicine, Virginia Commonwealth University, Richmond, Virginia (Ms Abbasi and Dr Walker).
Objective:
To investigate the associations between current chronic pain and cognition and current chronic head pain and cognition in individuals with traumatic brain injury (TBI).
Setting:
Community.
Participants:
A total of 1762 participants from the TBI Model Systems who endorsed experiencing current chronic pain and who completed the Current Chronic Pain survey.
Design:
Secondary analysis of a subset of data collected through a multi-site, cross-sectional observational cohort study.
Main Outcome Measures:
Cognition as measured by the Brief Test of Adult Cognition by Telephone (BTACT).
Results:
Individuals with TBI who reported current chronic pain exhibited lower cognitive performance compared to those who reported no pain. Among individuals who reported pain, greater pain intensity and pain interference were negatively associated with cognition, resulting in poorer cognitive performance. The negative association was even greater for individuals acknowledging chronic head pain compared to pain from other body locations.
Conclusion:
The negative association between current chronic pain and cognition for individuals with TBI indicates the need to consider pain intensity and pain interference as factors possibly influencing cognitive ability.
More Related Videos
10:52Chronic Constriction Injury of the Rat's Infraorbital Nerve IoN-CCI to Study Trigeminal Neuropathic Pain
Published on: September 21, 2015
05:38Author Spotlight: Utilizing Infraorbital Nerve Ligation in Mice for Investigating Trigeminal Neuropathic Pain and Treatment Strategies
Published on: March 8, 2024