Related Experiment Video
Updated: May 26, 2025
Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
Eosinophils and the Head and Neck
1Department of Pathology, Walter Reed National Miliary Medical Center, Bethesda, MD, USA.
Tissue eosinophilia, characterized by abundant eosinophils in tissues, is crucial for diagnosing head and neck disorders. This review covers eosinophil biology and common eosinophil-rich diseases in this region.
Area of Science:
- Pathology
- Histopathology
- Head and Neck Anatomy
Background:
- Tissue eosinophilia is a frequent histopathologic finding.
- Recognizing eosinophils aids in accurate diagnosis.
- The head and neck region harbors numerous eosinophil-rich disorders.
Purpose of the Study:
- To provide a comprehensive overview of eosinophil biology.
- To review eosinophil morphology, production, regulation, lifecycle, recruitment, function, and mediators.
- To summarize common non-neoplastic and neoplastic eosinophil-rich disorders in the head and neck.
Main Methods:
- Literature review.
- Synthesis of information on eosinophil biology.
- Categorization and summary of head and neck eosinophilic disorders.
Main Results:
- Eosinophils play diverse roles in health and disease.
- A spectrum of eosinophil-related conditions exists in the head and neck.
- Understanding eosinophil behavior is key to diagnosing these disorders.
Conclusions:
- Eosinophil biology is complex and multifaceted.
- Head and neck pathology frequently involves eosinophils.
- This review serves as a guide to eosinophil-rich disorders in the head and neck.
More Related Videos
05:17Fast and Specific Assessment of the Halogenating Peroxidase Activity in Leukocyte-enriched Blood Samples
Published on: July 28, 2016
07:00Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Related Concept Videos
01:18Cranial Part of Parasympathetic Division
The vagus nerve (cranial nerve X) alone accounts for approximately 75...
01:26Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
01:23Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
01:30Tonsillitis I: Introduction
Etiology
Three primary contributing factors have been identified.
01:30Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
01:19Veins of Head and Neck
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...