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Updated: May 26, 2025

One-anastomosis Gastric Bypass OAGB in Rats
Published on: November 10, 2018
Beyond Insulin: Modified OAGB in Low-BMI Insulin-Resistant and Non-compliant Type 2 Diabetic Patients
Kiranjot Singh Kular1, Shubhkaran Singh Gill1, Naveen Manchanda2
1Dayanand Medical College & Hospital, Ludhiana, India.
Background:
Metabolic surgery's role in lower-BMI patients with type 2 diabetes mellitus (T2DM) remains debated, particularly regarding long-term outcomes.
Methods:
This retrospective study analyzed 54 patients (BMI 24-30 kg/m2) with poorly controlled T2DM (HbA1c ≥ 10%) who underwent modified one anastomosis gastric bypass between 2016 and 2017. Primary outcomes included glycemic control, weight loss, and complications at 7 years.
Results:
Mean preoperative BMI was 26.76 ± 1.82 kg/m2, and HbA1c was 12.63 ± 1.67%. Follow-up rates were year 1 (54/54, 100%), year 3 (52/54, 96.3%), year 5 (48/54, 88.9%), and year 7 (36/38, 94.7% of eligible patients). At 7-year follow-up, mean HbA1c decreased to 6.17 ± 0.71% (p < 0.001), and %TWL was 13.1 ± 2.4%. Complete medication elimination occurred in 45 of 54 patients (83.3%) achieving HbA1c < 6.5%. No mortality or major complications were reported.
Conclusions:
Modified OAGB demonstrates sustained glycemic control and safety in lower-BMI patients with severe T2DM through 7 years with potential benefits of early surgical intervention.
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