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Related Concept Videos

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

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Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
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Autism Spectrum Disorder01:19

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Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
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Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
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Updated: May 26, 2025

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy
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Attention Deficit Hyperactivity Disorder in Children With Cerebral Palsy: A Case-Control Study.

Michele Zaman1, Tarannum Behlim2, Pamela Ng2

  • 1Department of Medicine, Queen's University, Ontario, Canada.

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|February 25, 2025
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Summary
This summary is machine-generated.

Attention deficit hyperactivity disorder (ADHD) is significantly more common in children with cerebral palsy (CP). This highlights the need to consider neurodevelopmental disorders in CP care.

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Area of Science:

  • Pediatric Neurology
  • Neurodevelopmental Disorders
  • Public Health Research

Background:

  • Cerebral palsy (CP) is the leading physical disability in children, frequently co-occurring with neurodevelopmental disorders (NDDs) like attention deficit hyperactivity disorder (ADHD).
  • Both CP and ADHD are influenced by complex genetic and environmental factors, significantly impacting a child's daily functioning and overall well-being.
  • Understanding the prevalence and associated factors of ADHD in children with CP is crucial for comprehensive care and intervention strategies.

Purpose of the Study:

  • To determine the prevalence of ADHD in school-aged children diagnosed with cerebral palsy (CP).
  • To investigate factors associated with ADHD in children with CP, including sex, socioeconomic status, epilepsy, prematurity, CP subtype, and motor function.
  • To compare ADHD prevalence in children with CP against a control group.

Main Methods:

  • A cross-sectional study utilizing linked data from a population-based CP registry and administrative health claims databases in Quebec, Canada.
  • Inclusion criteria: Children diagnosed with CP born between 1999 and 2002.
  • ADHD diagnosis was identified through International Classification of Diseases codes and ADHD medication prescriptions; statistical analyses (odds ratios, confidence intervals) were employed to explore associations.

Main Results:

  • The study included 302 children with CP and 6,040 matched controls.
  • ADHD prevalence was substantially higher in the CP cohort (38%) compared to controls (12%).
  • Multivariate analysis indicated that less severe motor impairment was significantly associated with higher odds of ADHD in children with CP (OR 2.02, 95% CI 1.07-3.94).

Conclusions:

  • Children with cerebral palsy exhibit a significantly higher prevalence of ADHD, supporting the concept of a neurodevelopmental overlap between these conditions.
  • The findings underscore the importance of screening for and managing NDDs, particularly ADHD, in the comprehensive care of children with CP.
  • Further research is warranted to elucidate the neurobiological underpinnings connecting CP and ADHD and their combined impact on health outcomes.