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An Orthotopic Bladder Cancer Model for Gene Delivery Studies

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Stage Migration in Urological Cancers in Germany during the COVID-19 Pandemic: Fact or Fiction?

Henning Bahlburg, Patricia Rausch¹, Matteo Silberg¹

¹Department of Urology, Marien Hospital Herne, Ruhr-University Bochum, Herne, Germany.

Urologia Internationalis

|February 25, 2025

Summary

The COVID-19 pandemic did not significantly alter cancer staging for prostate, bladder, or kidney cancers. Oncological outcomes and treatment standards remained stable for these urological malignancies.

Keywords:

Bladder cancer COVID-19 pandemic Kidney cancer Prostate cancer Stage migration

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Published on: September 16, 2019

Area of Science:

Urology
Oncology
Public Health

Background:

The COVID-19 pandemic significantly disrupted healthcare services globally.
Cancer treatment pathways were particularly affected, necessitating an evaluation of its impact on oncological care.
Urological malignancies represent a significant burden of cancer worldwide.

Purpose of the Study:

To investigate the potential impact of the COVID-19 pandemic on tumor stage migration.
To assess changes in tumor characteristics for prostate, bladder, and kidney cancers during the pandemic.
To evaluate if treatment standards and oncological outcomes were affected in urological cancer care.

Main Methods:

Retrospective analysis of patient and tumor characteristics.
Comparison of data from 2019 (pre-pandemic) and 2021 (mid-pandemic).
Focus on patients undergoing radical prostatectomy (prostate cancer), radical cystectomy (bladder cancer), or nephrectomy (kidney cancer).

Main Results:

No significant tumor stage migration was observed for prostate, bladder, or kidney cancers.
A decrease in high-risk prostate cancer (Gleason score ≥8) and lymph node metastases was noted.
Bladder cancer patients showed increased neoadjuvant chemotherapy use, and robot-assisted surgery increased across all studied malignancies.

Conclusions:

The COVID-19 pandemic did not lead to detectable stage migration in common urological cancers.
Therapeutic standards and oncological outcomes remained largely unchanged.
The findings suggest resilience in urological cancer care despite pandemic-related disruptions.