Related Experiment Video
Updated: May 25, 2025
14:56
An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
Published on: January 27, 2010
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Factors associated with poor pain experience after surgery.
Axel Maurice-Szamburski1, Romain Rozier2, Victor Gridel3
1Department of Anaesthesiology and Intensive Care Medicine, University Hospital Centre Nice Pasteur Hospital, Nice, Provence-Alpes-Côte d'Azur, France amszamburski@gmail.com.
Regional Anesthesia and Pain Medicine
|February 25, 2025
Summary
Intraoperative remifentanil and sufentanil use significantly predicts poor postoperative pain. Reassessing anesthetic strategies is crucial for improving patient outcomes and reducing complications.
Area of Science:
- Anesthesiology
- Pain Management
- Surgical Outcomes
Background:
- Postoperative pain significantly impacts patient recovery and satisfaction.
- Identifying predictors of poor pain experience is essential for optimizing care.
Purpose of the Study:
- To identify patient-related and procedural factors associated with poor postoperative pain experience.
- To analyze the impact of intraoperative anesthetic agents on pain outcomes.
Main Methods:
- Secondary analysis of 971 adult patients undergoing elective surgery.
- Assessment of preoperative anxiety (APAIS) and pain, sleep, well-being (VAS).
- Primary endpoint: patient experience (EVAN-G) on postoperative day 1; poor pain defined as <25th percentile.
Main Results:
- 27.9% of patients reported poor pain experience.
- Intraoperative remifentanil/sufentanil use was a strong predictor (OR 26.96).
- Factors associated with lower poor pain: older age, premedication, orthopedic surgery. Predictors of poor pain: ASA 3 status, postoperative anxiolytics, amnesia, higher VAS pain, lower well-being.
Conclusions:
- Intraoperative remifentanil and sufentanil are independently linked to worse postoperative pain.
- Findings suggest a need to re-evaluate intraoperative analgesic strategies.
- Optimizing anesthesia protocols can improve patient outcomes and reduce complications.
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