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MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...

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Related Experiment Video

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Automated Extraction of Key Entities from Non-English Mammography Reports Using Named Entity Recognition with Prompt

Zafer Akcali1,2, Hazal Selvi Cubuk3, Arzu Oguz2

  • 1Department of Medical Informatics, Faculty of Medicine, Baskent University, Ankara 06790, Türkiye.

Bioengineering (Basel, Switzerland)
|February 26, 2025
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Summary

This study demonstrates that prompt-based named entity recognition (NER) using large language models effectively extracts clinical information from Turkish mammography reports, outperforming other few-shot methods.

Keywords:
clinicomicsmachine learningmammographynamed entity recognition (NER)natural language processing (NLP)prompt engineeringradiology reports

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Area of Science:

  • Natural Language Processing (NLP)
  • Medical Informatics
  • Artificial Intelligence in Healthcare

Background:

  • Named Entity Recognition (NER) is crucial for extracting clinical information from text.
  • Existing NER models often lack robust support for non-English languages, limiting their global applicability.
  • Turkish mammography reports present a specific challenge due to limited NLP resources.

Purpose of the Study:

  • To investigate a prompt-based NER approach using Google's Gemini 1.5 Pro for Turkish clinical text.
  • To evaluate the model's efficacy in extracting key clinical entities from mammography reports.
  • To assess the performance of many-shot learning in a low-resource language setting.

Main Methods:

  • Employed a prompt-based NER strategy with Google's Gemini 1.5 Pro (1.5-million-token context window).
  • Utilized many-shot learning, incorporating 165 examples within a 26,000-token prompt.
  • Focused on extracting five key entities: anatomy (ANAT), impression (IMP), observation presence (OBS-P), absence (OBS-A), and uncertainty (OBS-U) from 85 unannotated reports.

Main Results:

  • Achieved high accuracy with macro-averaged F1 scores of 0.99 (relaxed match) and 0.84 (exact match).
  • Relaxed matching yielded F1 scores of 0.99 for ANAT, 0.99 for IMP, 1.00 for OBS-P, 1.00 for OBS-A, and 0.99 for OBS-U.
  • Exact matching achieved F1 scores of 0.88 for ANAT, 0.79 for IMP, 0.78 for OBS-P, 0.94 for OBS-A, and 0.82 for OBS-U.

Conclusions:

  • Many-shot prompt engineering with LLMs is an effective method for clinical information extraction in under-resourced languages.
  • This approach demonstrates superior performance compared to zero-shot and other few-shot methods.
  • Potential to significantly enhance clinical workflows and research in multilingual healthcare settings.