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Colorectal Neoplasia in Inflammatory Bowel Disease
Eman Al Sulais1, Turki AlAmeel1, Maram Alenzi2
1Department of Medicine, King Fahad Specialist Hospital, Dammam 32253, Saudi Arabia.
Abstract:
Patients with inflammatory bowel disease (IBD), including ulcerative colitis and colonic Crohn's disease, are at an increased risk of developing colonic dysplasia and neoplasia. Multiple risk factors have been identified that increase the risk of colonic neoplasia in IBD, including but not limited to underlying disease extent, severity, duration, and concomitant primary sclerosing cholangitis. The overall risk of colonic neoplasia in IBD is decreasing but surveillance is still warranted in patients with high-risk features. In this review, we will discuss the epidemiology, pathogenesis, risk factors, approach to surveillance, and management of colonic neoplasia in IBD.
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