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Trends in Clinical Cardiac Photon-Counting Detector CT Research: A Comprehensive Bibliometric Analysis
Arosh S Perera Molligoda Arachchige1, Federica Catapano1,2, Costanza Lisi1,2
1Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20090 Milan, Italy.
Abstract:
Photon-counting detector computed tomography (PCD-CT) represents a significant advancement in radiological imaging, offering substantial potential for cardiac applications that remain partially underexplored. This bibliometric analysis investigates the evolution and current clinical application of cardiac PCD-CT by examining research trends from 2019 to 2024. The analysis aims to understand the development of this technology, its clinical implications, and future directions. A comprehensive literature search was conducted using databases such as PubMed, EMBASE, Scopus, and Google Scholar, yielding 984 records. After removing duplicates and applying inclusion criteria, 81 studies were included in the final analysis. These studies primarily focused on coronary artery calcium scoring, coronary atherosclerotic plaque assessment, and coronary artery stenosis quantification. The findings indicate a significant upward trend in the number of publications, peaking in 2023. The bibliometric analysis revealed that the USA, Germany, and Switzerland are the leading contributors to PCD-CT research, with prominent institutions like the Mayo Clinic and the University of Zurich driving advancements in the field. The NAEOTOM Alpha by Siemens Healthineers, being the only commercially available PCD-CT model, highlights its central role in cardiac imaging studies. Funding for PCD-CT research came from various sources, including industry leaders like Siemens and Bayer, as well as governmental and academic institutions. The analysis also identified several challenges that PCD-CT research faces, including the need for larger patient cohorts and broader geographical representation. In conclusion, the rapid growth of cardiac PCD-CT research underscores its transformative potential in clinical practice. Continued investment, collaboration, and extensive research are essential to fully harness the benefits of PCD-CT.
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