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Refining Glaucoma Management: Korean Population-Specific Findings from Visual Field and Optical Coherence Tomography
Sun Jung Lee1, Sung Hun Jang2, Jae Kyung Kim1
1Department of Biomedical Laboratory Science, College of Health and Welfare, Dankook University, Cheonan-si 31116, Republic of Korea.
Biomedicines
|February 26, 2025
Summary
Age and sex impact glaucoma progression, with males showing faster decline. Optical coherence tomography (OCT) and visual field tests reveal age-related changes, informing personalized Korean glaucoma management.
Area of Science:
- Ophthalmology
- Medical Diagnostics
Background:
- Establishing glaucoma evaluation standards requires understanding demographic influences.
- Korean glaucoma patient data is essential for tailored diagnostic and management protocols.
Purpose of the Study:
- To analyze visual field tests and optical coherence tomography (OCT) results in Korean patients.
- To determine the correlation between glaucoma test results and patient demographics (age, sex).
- To provide a reference for establishing Korean glaucoma evaluation standards.
Main Methods:
- Analysis of 1510 visual field tests and 1337 OCT tests from a national hospital in Seoul.
- Utilized Humphrey automated visual field testing and OCT measurements.
- Classified glaucoma stages (early, moderate, advanced) based on mean deviation (MD) values and performed statistical analyses.
Main Results:
- Visual field index and MD values decreased with age in both sexes, more significantly in males.
- Optical coherence tomography (OCT) showed age-related thinning of the ganglion cell-inner plexiform layer (GCIPL) and retinal nerve fiber layer (RNFL).
- Females maintained thicker GCIPL and RNFL compared to males until their 60s.
Conclusions:
- Age and sex are associated with glaucoma progression.
- Findings support the combined use of visual field testing and OCT for glaucoma diagnosis in Korea.
- Highlights the importance of early detection and personalized treatment for effective glaucoma management in the Korean population.
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