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Strain comparison of synaptic density in hippocampal CA1 of aged rats
Neurobiology of Aging
|January 1, 1985
Abstract:
Synaptic density in hippocampal CA1 stratum radiatum was studied in two different strains of rat at 3 and 24-28 months of age. Neither Fischer 344 nor Sprague-Dawley rodents showed any age-related loss of synapses. These data support the contention that synapse loss with age is not a generalized phenomenon in the mammalian CNS.