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Updated: May 25, 2025
Comprehensive DNA Methylation Analysis Using a Methyl-CpG-binding Domain Capture-based Method in Chronic Lymphocytic Leukemia Patients
Published on: June 16, 2017
Genome-Wide In Silico Analysis of Leucine-Rich Repeat R-Genes in Perilla citriodora: Classification and Expression
Seon-Hwa Bae1, Yedomon Ange Bovys Zoclanclounon2, Gyu-Hwang Park3
1Fruit Research Division, National Institute of Horticultural and Herbal Science, Rural Development Administration, Iseo-myeon, Wanju-gun 55365, Republic of Korea.
Background:
Resistance (R) genes are crucial for defending Perilla against pathogens like anthracnose, downy mildew, and phytophthora blight. Nucleotide-binding site leucine-rich repeat (NBS-LRR) genes, the largest R-gene family, play a central role in immunity. This study aimed to identify and characterize NBS-LRR genes in P. citriodora 'Jeju17'.
Methods:
Previously conducted genome-wide data for 'Jeju17' were analyzed in silico to identify NBS-LRR genes.
Results:
A total of 535 NBS-LRR genes were identified, with clusters on chromosomes 2, 4, and 10. A unique RPW8-type R-gene was located on chromosome 7.
Conclusions:
This study provides insights into the NBS-LRR gene family in 'Je-ju17', highlighting its role in disease resistance and evolutionary dynamics. By identifying can-didate R-genes, this research supports breeding programs to develop disease-resistant cultivars and improves our understanding of plant immunity.
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