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Dynamic Analysis of the Voiding Patterns in Bladder Diaries Collected in Clinical Practice.
Victor P Andreev1, Wade A Bushman2, Jeffrey P Weiss3
1Arbor Research Collaborative for Health, Ann Arbor, MI, USA.
Neurourology and Urodynamics
|February 26, 2025
Summary
Bladder filling rate significantly drives urinary urgency and frequency in patients. Understanding these patterns can lead to better treatments for urinary symptoms.
Area of Science:
- Urology
- Clinical Medicine
- Data Science
Background:
- Urinary urgency and frequency are common symptoms impacting quality of life.
- Understanding the underlying voiding patterns is crucial for effective management.
Purpose of the Study:
- To analyze voiding patterns in clinical patients using bladder diaries.
- To identify mechanisms and phenotypes of urinary urgency.
Main Methods:
- Dynamic analysis of bladder diaries from 227 patients.
- Intra-subject correlation analyses of voiding variables.
- Multivariable linear regression and patient clustering.
Main Results:
- Five distinct patient clusters based on voiding patterns were identified.
- Bladder filling rate strongly correlated with urinary urge intensity.
- Bladder filling rate was the primary driver of urinary frequency and urgency.
Conclusions:
- Bladder filling rate is a key factor in urinary urgency and frequency.
- Further research is needed to address peaks in bladder filling rate and develop targeted treatments.
