WAYS TO IMPROVE THE RESULTS OF SURGICAL TREATMENT OF DIFFUSE TOXIC GOITER

Y Mukash1, N Omarov1, M Aimagambetov1

  • 11Department of Hospital Surgery, Anesthesiology and Reanimatology, Non-Commercial Joint-Stock Company "Semey Medical University" (NCJSC «SMU»), Republic of Kazakhstan.

Georgian Medical News
|February 26, 2025
PubMed
Abstract

Insights

New surgical techniques for diffuse toxic goiter (DTG) significantly reduce intraoperative complications. This approach lowers risks of nerve injury and bleeding, improving patient outcomes and recovery times.

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Vascular Surgery

Background:

  • Diffuse toxic goiter (DTG) treatment necessitates optimal surgical methods to prevent intraoperative complications.
  • Existing surgical approaches for DTG carry risks, prompting research into improved techniques.

Purpose of the Study:

  • To develop and evaluate novel methods for minimizing intraoperative complications in diffuse toxic goiter surgery.
  • To assess the efficacy of a combined surgical approach including laryngeal nerve protection, specialized instrumentation, and thyroid artery embolization.

Main Methods:

  • A comparative study involving 85 patients with DTG from 2017-2020.
  • The main group (39 patients) underwent surgery using a laryngeal nerve protection method, a recurrent laryngeal nerve removal tool, and thyroid artery embolization.
  • The control group (46 patients) received traditional surgical intervention.

Main Results:

  • The main group showed significantly reduced hemorrhagic discharge (16.4±7.4 ml vs. 36.1±8.4 ml) and shorter drainage duration.
  • Vocal cord paresis occurred in 4.3% of the control group, versus 0% in the main group.
  • Hypoparathyroidism rates were lower in the main group (2.5% vs. 8.6%), and no postoperative bleeding was observed.
  • Inpatient stay was shorter in the main group (4.2±0.6 days vs. 6.1±0.8 days).

Conclusions:

  • The combined use of laryngeal nerve protection, specialized tools, and preoperative thyroid artery embolization effectively reduces intraoperative complications in DTG surgery.
  • This integrated approach leads to a 26% reduction in surgery duration and a 52.5% decrease in blood loss.
  • The novel methods improve immediate and long-term surgical outcomes, avoiding complications like recurrent nerve injury and bleeding.

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