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Associations between asthma and Life's Essential 8: a cross-sectional study
1Department of Respiratory and Critical Care Medicine, WuJin Hospital Affiliated with Jiangsu University, WuJin Clinical College of Xuzhou Medical University, Changzhou, Jiangsu, China.
Frontiers in Medicine
|February 26, 2025
Summary
Higher Life's Essential 8 (LE8) scores are linked to lower asthma risk. Improving these cardiovascular health metrics may help reduce asthma prevalence.
Area of Science:
- Public Health
- Cardiovascular Health
- Respiratory Medicine
Background:
- Asthma is a significant respiratory condition influenced by various factors.
- The American Heart Association's Life's Essential 8 (LE8) promotes cardiovascular health.
- The relationship between LE8 components and asthma risk is not well-established.
Purpose of the Study:
- To investigate the association between Life's Essential 8 (LE8) scores and asthma prevalence.
- To determine if LE8 serves as a protective factor against asthma development.
Main Methods:
- Analysis of data from the National Health and Nutrition Examination Survey (NHANES) spanning 2001-2018.
- Utilized multiple logistic regression, restricted cubic spline (RCS), and subgroup analyses.
- Included 3,360 participants diagnosed with asthma.
Main Results:
- A negative correlation was found between LE8 scores and asthma prevalence (OR per 10-point increase: 0.85; 95% CI: 0.82-0.88).
- Moderate and high LE8 scores were associated with significantly reduced asthma risk (ORs: 0.59 and 0.48, respectively).
- Non-linear associations were observed between LE8 scores and asthma prevalence.
Conclusions:
- Life's Essential 8 (LE8) components are associated with asthma prevalence.
- Higher adherence to LE8 recommendations may contribute to a reduction in asthma incidence.
- Further research into LE8's role in asthma prevention is warranted.
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