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Related Experiment Video

Updated: May 25, 2025

Modeling Stroke in Mice - Middle Cerebral Artery Occlusion with the Filament Model

Modeling Stroke in Mice - Middle Cerebral Artery Occlusion with the Filament Model

Published on: January 6, 2011

Synthetic Data for the Get With The Guidelines-Stroke Registry.

Lanjing Wang¹, Vihaan Manchanda¹, Holly Picotte¹

¹American Heart Association Dallas TX USA.

Journal of the American Heart Association

|February 26, 2025

Summary

This summary is machine-generated.

Researchers created a synthetic dataset from the American Heart Association

Keywords:

American Heart Association Get With The Guidelines Stroke

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Area of Science:

Cardiovascular research
Health informatics
Data science

Background:

The American Heart Association's Get With The Guidelines-Quality Improvement registry contains millions of real-world cardiovascular and stroke records.
Access to this data is crucial for research but limited due to privacy concerns.

Purpose of the Study:

To generate a privacy-preserving synthetic dataset from the Get With The Guidelines-Stroke registry.
To facilitate broader access and exploration of real-world stroke data for research.

Main Methods:

Randomly sampled 1000 records from 7.8 million registry records (2005-2021).
Shifted time variables and replaced patient identifiers to ensure privacy.
Compared demographic and clinical variable distributions between original and synthetic data.

Main Results:

The synthetic dataset closely mirrored the original data's distributions for demographics (age, race, sex).
Key stroke metrics, including door-to-needle time and time to thrombolytic therapy, showed similar distributions.
The synthetic data successfully preserved critical data characteristics.

Conclusions:

Generated synthetic data provides a viable, privacy-protected alternative for accessing real-world stroke data.
This open-access dataset empowers researchers to explore cardiovascular and stroke data more freely.
Facilitates wider research and potential advancements in stroke care.