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Prevalence of Hypocalcemia in Pediatrics With Lower Respiratory Tract Infections

Usha Sree Puneem1, Vanitha Rani Nagasubramanian2, Bhima Sridevi3

  • 1Department of Pharmacy Practice, Jayamukhi College of Pharmacy, Narasampet, India.

Clinical Pediatrics
|February 26, 2025
PubMed

Insights

Calcium deficiency is common in children with lower respiratory tract infections (LRTIs). Higher body weight is linked to calcium imbalance in these pediatric patients, underscoring the need for monitoring.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Biochemistry

Background:

  • Lower respiratory tract infections (LRTIs) are a significant cause of pediatric morbidity.
  • Electrolyte imbalances, including calcium, can complicate infectious diseases.

Purpose of the Study:

  • To evaluate blood calcium levels in children diagnosed with LRTIs.
  • To identify factors associated with calcium dysregulation in this population.

Main Methods:

  • Retrospective observational study design.
  • Analysis of 225 patient records from September 2023 to February 2024.
  • Assessment of blood calcium, chloride, and potassium levels, along with immunization status and body mass.

Main Results:

  • Hypocalcemia was prevalent in 44.8% of pediatric LRTI patients.
  • A significant negative correlation was found between normal calcium levels and body mass (r=-0.295, P=.001).
  • Immunization status did not significantly impact hypocalcemia risk (OR=1.04, P>.05).

Conclusions:

  • Hypocalcemia is a common finding in children with LRTIs.
  • Higher body weight is associated with an increased risk of calcium imbalance.
  • Regular monitoring of blood calcium levels is recommended for pediatric patients with LRTIs.

Keywords:
LRTIshypocalcaemiapediatricsprevalence

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