Related Experiment Video
Updated: May 25, 2025

Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method
Published on: July 19, 2019
Photo-ejected ligands hyperpolarized by parahydrogen in reversible exchange
Emily E Brown1, Rielly J Harrison1, Dmytro Havrylyuk1
1Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27965-8204, USA. fncastel@ncsu.edu.
Abstract:
Hyperpolarization derived from signal amplification by reversible exchange (SABRE) is valued for its relative simplicity among hyperpolarization approaches. Here, we demonstrate that photoejection of the ligands pyridazine and pyrazine from prodrug Ru(II) polypyridyl complexes offers a new modality for activating SABRE hyperpolarization, achieving enhancements of over 3200-fold.
Related Concept Videos
Photochemical Electrocyclic Reactions: Stereochemistry
Selection Rules: Photochemical Activation
Deactivation Processes: Jablonski Diagram
Hydrogen Bonds
ortho–para-Directing Deactivators: Halogens
Molecular Orbital Theory II
Thermal and Photochemical Electrocyclic Reactions: Overview

