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Related Concept Videos

Neurons: The Axon01:21

Neurons: The Axon

3.1K
Axons are long, cytoplasmic processes of nerve cells capable of propagating electrical impulses known as action potentials. The cytoplasm or axoplasm of an axon contains neurofibrils, neurotubules, small vesicles, lysosomes, mitochondria, and various enzymes, all encased within the axolemma, the plasma membrane of the axon.
The axon attaches to the cell body at a cone-shaped elevation called the axon hillock. The initial part of the axon, closest to the hillock, is known as the initial segment....
3.1K
Action Potentials01:41

Action Potentials

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Overview
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Action Potential01:31

Action Potential

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Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they...
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Propagation of Action Potentials01:23

Propagation of Action Potentials

5.0K
The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
5.0K
Spinal Cord: Information Processing01:10

Spinal Cord: Information Processing

1.1K
The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
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Functions of the Nervous System01:18

Functions of the Nervous System

3.2K
The nervous system is responsible for coordinating and regulating the body's functions. It functions through three main processes: sensory, integrative, and motor processes. Sensory function involves the detection and transmission of information about internal and external stimuli from sensory receptors to the CNS. The CNS processes this information through an integrative function, where it interprets and makes decisions based on the incoming sensory information. Finally, the motor function...
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RABR-1, an atypical Rab-related GTPase, cell-nonautonomously restricts somatosensory dendrite branching.

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Related Experiment Video

Updated: May 25, 2025

Axon Stretch Growth: The Mechanotransduction of Neuronal Growth
11:46

Axon Stretch Growth: The Mechanotransduction of Neuronal Growth

Published on: August 10, 2011

16.8K

Watching axons on the move.

Maria I Lazaro-Pena1, Carlos A Diaz-Balzac1

  • 1Division of Endocrinology, Diabetes and Metabolism, University of Rochester Medical Center, Rochester, United States.

Elife
|February 26, 2025
PubMed
Summary
This summary is machine-generated.

Netrin guides nerve cell axons using touch (haptotaxis) at close range and chemical signals (chemotaxis) over long distances. This dual mechanism is crucial for precise neural wiring.

Area of Science:

  • Neuroscience
  • Developmental Biology

Background:

  • Axon guidance is essential for forming functional neural circuits.
  • Netrin is a secreted protein implicated in neuronal development.
Keywords:
C. elegansUNC-40/DCCUNC-6/netrinaxon guidancechemotaxisdevelopmental biologyhaptotaxisneuroscience

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