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Perioperative decline in isometric knee extension force is a predictor of unplanned readmission within 1 year in patients with colorectal cancer

  • 0Department of Rehabilitation, Kamiiida Daiichi General Hospital, 2-70 Kamiiida-kitamachi, Kita-ku, Nagoya, Aichi, 462-0802, Japan; Faculty of Rehabilitation and Care, Seijoh University, 2-172 Fukinodai, Tokai, Aichi, 476-8588, Japan.
European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology +

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February 26, 2025

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February 26, 2025

View abstract on PubMed

Summary

This summary is machine-generated.

A decline in isometric knee extension force (IKEF) after surgery is linked to unplanned readmission (UR) in colorectal cancer (CRC) patients. Monitoring IKEF can help predict and prevent UR within a year post-surgery.

Area Of Science

  • Oncology
  • Geriatrics
  • Rehabilitation Medicine

Background

  • Perioperative physical function is crucial for colorectal cancer (CRC) patient recovery.
  • Unplanned readmission (UR) within one year is a significant concern for CRC survivors.
  • Understanding predictors of UR can optimize post-surgical care pathways.

Purpose Of The Study

  • To investigate the association between perioperative physical function and 1-year UR in CRC patients.
  • To identify specific physical function metrics that predict readmission risk.
  • To inform targeted rehabilitation strategies for CRC patients.

Main Methods

  • Retrospective cohort study of 155 CRC patients undergoing surgery.
  • Physical function assessed via isometric knee extension force (IKEF) and 6-minute walk distance.
  • Decline ratio of IKEF calculated; propensity score matching used to control for confounders.

Main Results

  • A significant difference in IKEF decline ratio was found between patients with and without UR (p=0.007).
  • In propensity score-matched patients, a decline in IKEF (≤ -18.8%) was significantly associated with UR (p=0.003).
  • Cox analysis revealed a hazard ratio of 9.26 for UR with IKEF decline (p=0.035).

Conclusions

  • Decline in isometric knee extension force is a significant predictor of 1-year unplanned readmission in colorectal cancer patients.
  • IKEF monitoring may aid in identifying high-risk patients for targeted interventions.
  • This finding supports the integration of physical function assessments into routine post-operative CRC care.

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