Related Experiment Video
Updated: Aug 19, 2026

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
Published on: July 10, 2012
What's new in bronchial obstruction? Experimental pathology and clinico-pathologic correlation
Abstract:
The aim of general pathology, which following Virchow also should be pathophysiology (and pathobiochemistry), is to elucidate general principles and main mechanisms of diseases. Conceptions like reticulo-endothelial system or coronary insufficiency, inflammations and its mediators, modes of metastasis and many comparable topics are examples of this type of scientific approach, and its tools are careful morphological analysis as well as experimental work of different kinds. In pulmonary pathology the obstruction of airways is one of the most important pathogenetical pathways. Among a broad spectrum of pulmonary diseases it is the main symptom of a developing chronic obstructive pulmonary disease (COPD) and the outstanding cause of cardio-respiratory failure. In German literature the last comprehensive survey on general respiratory pathology was written some twenty years ago and a review of the main techniques of investigation was given at about the same time. Since then - parallel to the invention of new measuring techniques and to the progress in clinical pathophysiology - a rapid further development in the understanding of the pathology of respiratory disorders has taken place, particularly in connection with research in chronic bronchitis and emphysema. Some examples of this development and of the present state of discussion will be reviewed briefly.
More Related Videos
Related Concept Videos
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due to...
Chronic Obstructive Pulmonary Disease I: Introduction
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

