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Updated: May 25, 2025

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Managing childhood asthma with an eye toward environmental, social, and behavioral features
Emily H Skeen1, Katharine L Hamlington1, Heather H De Keyser1
1Pediatric Pulmonary and Sleep Medicine Section, Department of Pediatrics, Breathing Institute, Anschutz Medical Campus, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado.
Insights
This review highlights non-pharmacologic asthma management strategies, emphasizing environmental factors and social determinants of health to address health disparities and improve asthma control beyond traditional anti-inflammatory approaches.
Area of Science:
- Pulmonary Medicine
- Health Equity Research
- Public Health
Background:
- Asthma management discussions often prioritize pharmacologic treatments, potentially overlooking crucial non-therapeutic factors.
- Current anti-inflammatory therapies primarily target the T2 component of airway inflammation, leaving other inflammatory pathways under-addressed.
- Growing recognition of health disparities necessitates a broader approach to asthma management.
Purpose of the Study:
- To review and provide tools for the non-pharmacologic aspects of asthma management.
- To emphasize the role of environmental exposures, social determinants of health, and behaviors in asthma.
- To promote shared decision-making for equitable asthma care.
Main Methods:
- Literature review focusing on non-pharmacologic interventions in asthma.
- Analysis of factors contributing to asthma persistence, progression, and comorbidities.
- Identification of tools for integrating non-pharmacologic strategies into clinical practice.
Main Results:
- Non-pharmacologic factors like environmental exposures and social determinants significantly impact asthma outcomes.
- Existing therapeutic approaches have limitations in addressing the full spectrum of airway inflammation.
- Shared decision-making models can incorporate these broader factors into patient care.
Conclusions:
- A comprehensive asthma management strategy must integrate non-pharmacologic interventions alongside pharmacologic treatments.
- Addressing social determinants and environmental factors is crucial for achieving health equity in asthma care.
- Further research and clinical tools are needed to effectively manage the multifaceted nature of asthma.
Abstract:
Discussions on asthma management tend to focus on the therapeutic aspects when updates on asthma strategies are released. However, many other components of asthma management are now receiving increased attention, as we seek to make right on health disparities and strive toward health equity. In addition, with the therapeutic aspects of asthma, we now realize that our anti-inflammatory approaches largely address the high T2 component of airway inflammation. However, we know very little about what we can do to control the other inflammatory features that contribute to asthma. Factors, such as environmental exposures, social determinants of health, and risk-taking behaviors may be at the root of asthma persistence, progression, and comorbidities. We will continue to learn methods to identify these issues and draw them into a shared decision-making approach for dialogue with patients and their caregivers. This review provides information and tools to address the nonpharmacologic aspects of asthma management.
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