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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

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A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
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Cystic Fibrosis: Pathogenesis01:23

Cystic Fibrosis: Pathogenesis

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Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
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Papillary Dermis01:11

Papillary Dermis

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
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Tissue Membranes01:27

Tissue Membranes

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A tissue membrane is a thin layer of cells that covers the outside of the body, the organs, internal passageways that lead to the exterior of the body, and the lining of the moveable joint cavities. There are two basic types of tissue membranes— connective tissue and epithelial membranes.
Connective Tissue Membranes
The connective tissue membrane is formed solely from connective tissue. These membranes encapsulate organs, such as the kidneys, and line our movable joints. A synovial...
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Sweat gland carcinoma: a comprehensive review Part I: sweat gland carcinomas arising de novo.

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Using spaced repetition to teach histopathology significantly improves diagnostic skills: A randomized within-participant evaluation.

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Prognostic classification of skin adnexal carcinomas: Results from a prospective study of 980 patients in the French CARADERM network.

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Related Experiment Video

Updated: May 25, 2025

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
10:45

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

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[Case #4. Cutaneous cysts].

Thibault Kervarrec1

  • 1Service d'anatomie et cytologie pathologiques, hôpital Trousseau, université de Tours, centre hospitalier universitaire de Tours, 37170 Chambray-lès-Tours cedex France.

Annales De Pathologie
|February 26, 2025
PubMed
Summary

This session reviews common skin cystic neoplasms, including malformative, acquired, and sweat-related types. It also covers genetic syndromes and malignant tumors mimicking cysts.

Area of Science:

  • Dermatology
  • Pathology
  • Oncology

Background:

  • Cystic neoplasms are common skin findings.
  • Classification includes malformative, acquired epidermal/folliculo-sebaceous, and sweat differentiation cysts.
  • Distinguishing cystic sweat lesions from tumors with cystic changes is crucial.

Purpose of the Study:

  • To present frequent skin cystic lesions.
  • To discuss cystic neoplasms associated with genetic syndromes, including cancer predisposition.
  • To highlight malignant tumors that can mimic cystic lesions.

Main Methods:

  • Review of common cystic neoplasms.
  • Discussion of associations with genetic syndromes.
  • Differential diagnosis of malignant tumors simulating cysts.
Keywords:
CutaneousCutanésCystsKystesPeauSkin

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Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
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Main Results:

  • Categorization of cystic neoplasms into malformative, acquired, and sweat-related types.
  • Identification of specific genetic syndromes linked to cystic neoplasms.
  • Recognition of malignant tumors presenting as cystic lesions.

Conclusions:

  • Understanding the classification of skin cysts is essential for diagnosis.
  • Awareness of genetic syndromes and malignant mimics improves patient management.
  • Accurate differentiation aids in appropriate treatment strategies for skin cystic neoplasms.