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Computer controlled microwave system for clinical hyperthermia.

P Nilsson, B Persson

    Physics in Medicine and Biology
    |April 1, 1985
    PubMed
    Summary
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    A new microwave hyperthermia system uses 915 MHz applicators to heat superficial tumors. This system, controlled by a microcomputer and using pulsed irradiation, has treated 80 tumors.

    Area of Science:

    • Oncology
    • Medical Physics
    • Biomedical Engineering

    Background:

    • Hyperthermia, the application of heat to tissues, is an established adjuvant therapy in oncology.
    • Previous microwave hyperthermia systems faced challenges with applicator design and temperature control.

    Purpose of the Study:

    • To describe a newly developed clinical hyperthermia system for treating superficial tumors.
    • To detail the system's technical specifications and its application in combination with radiotherapy.

    Main Methods:

    • Direct-contact applicators operating at 915 MHz ISM microwave frequency.
    • Microcomputer control system integrating temperature measurements from thermistor probes.
    • Pulsed irradiation technique to minimize microwave-temperature probe interaction.

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    Main Results:

    • The system effectively delivers heat to superficial tumors up to approximately 3 cm depth.
    • Successfully treated 80 superficial tumors in combination with radiotherapy up to July 1984.
    • The system represents a refinement of an earlier prototype operating at 2450 MHz.

    Conclusions:

    • The described 915 MHz microwave hyperthermia system is suitable for clinical application.
    • The system's design, incorporating microcomputer control and pulsed irradiation, enhances therapeutic efficacy and safety.
    • Combined hyperthermia and radiotherapy show promise for superficial tumor treatment.