Related Experiment Video
Updated: May 25, 2025

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay
Published on: July 26, 2022
Pathogenesis of Orofacial Pain Based on Brain Circuits
1Department of Psychiatric Internal Medicine, Sunlight Brain Research Center, Hofu, Yamaguchi, Japan.
Abstract:
Orofacial pain is comprised of three distinct components: sensory, perception, and experience or memory. Each of these components is associated with its own specific brain circuit, thereby classifying orofacial pain into three distinct circuits: "peripheral pain," "brain network pain," and "memorized pain." Individuals afflicted with chronic orofacial pain of unknown etiology exhibit characteristics indicative of both brain network pain and memorized pain, necessitating a biopsychosocial approach that takes into account psychosocial factors in addition to the sensory aspects of pain.
Related Concept Videos
Pain
Nociception
Olfactory Receptors: Location and Structure
Physiology of Smell and Olfactory Pathway
The olfactory...
Blood and Nerve Supply to the Bones
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Analgesia and Pain Management

