Related Experiment Video
Updated: May 25, 2025
Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit
Published on: September 6, 2024
Role of the peripheral perfusion index in children with bronchial asthma
Hatice BayarAçık1, Nuh Yilmaz2, Ahmet Kan3
1Department of Pediatrics, Sanko University Hospital, Gaziantep, Turkey.
Insights
Peripheral perfusion index (PI) can help diagnose asthma exacerbations in children. Higher PI values in children with asthma indicate severity and aid in hospitalization decisions.
Area of Science:
- Pediatric Pulmonology
- Medical Diagnostics
- Noninvasive Monitoring
Background:
- Peripheral perfusion index (PI) is a noninvasive measure of peripheral blood volume and perfusion status.
- Asthma exacerbations require accurate classification and timely treatment for optimal patient outcomes.
Purpose of the Study:
- To investigate the relationship between peripheral perfusion index (PI) measurements and the classification and treatment of pediatric bronchial asthma exacerbations.
- To evaluate the diagnostic and prognostic value of PI in children presenting with asthma symptoms.
Main Methods:
- A prospective study involving children aged 5-12 years with and without asthma exacerbations.
- Recording of vital signs, oxygen saturation, and PI values before and after nebulizer therapy.
- Utilizing Receiver Operating Characteristic (ROC) curve analysis to determine the efficacy of PI in diagnosing asthma exacerbations and predicting hospitalization needs.
Main Results:
- Pretreatment PI values were significantly higher in children with asthma compared to healthy controls (p=0.001).
- ROC analysis demonstrated a high area under the curve (AUC=0.842) for a PI cutoff of 2.25 in diagnosing asthma exacerbations (p=0.001).
- ROC analysis indicated a significant AUC of 0.830 for a PI cutoff of 3.25 in determining the need for hospitalization (p=0.020).
Conclusions:
- Peripheral perfusion index (PI) is a valuable parameter for diagnosing asthma exacerbations in children.
- PI measurements can assist in making informed hospitalization decisions for pediatric patients with asthma symptoms.
Objective:
Peripheral perfusion index (PI) is noninvasive method measuring peripheral blood volume in numerical form and indicating perfusion status. In this study, we have investigated whether the relationship between the measurements of PI and definition of bronchial asthma exacerbation classification and treatment.
Methods:
This prospective study included in aged 5-12 years children applied to the hospital between January 2020 and June 2020. They were divided into two groups as patients who presented bronchial asthma symptoms and the control group who were selected as children applied to the hospital for routine healthy child follow-up. The severity of the asthma exacerbations was evaluated. Before administering nebulizer therapy, vital signs, oxygen hemoglobin saturation and PI values were recorded. Appropriate nebulizer treatment was initiated for the severity of exacerbation and subsequent changes in the PI values were recorded.
Results:
Pretreatment PI values were higher in children with asthma than those in healthy children (p = 0.001). The PI measurements of the patients for diagnosing asthma exacerbation showed a statistically significant area under the ROC curve (p = 0.001), and AUC (0.842) values of the 2.25 cutoff point of the PI value were sufficiently high. In the ROC analysis conducted to determine the need for hospitalization in patients presented with asthma exacerbations, the area under the curve was statistically significant (p = 0.020), and AUC (0.830) values of the 3.25 cutoff point of the PI value were sufficiently high.
Conclusions:
The PI measured in patients presented with asthma symptoms may use a valuable parameter for the diagnosing of asthma exacerbations and making hospitalization decisions.
Related Concept Videos
01:17Assessment of Diffusion and Perfusion
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
01:17Measurement of Blood Pressure