Perspectives on aerosol inhalability: concepts and applications

Area of Science:

• Aerosol science
• Occupational hygiene
• Environmental health

Background:

• Particle inhalation efficiency significantly alters inhaled air composition compared to ambient air.
• Inaccurate air sampling without inhalability adjustments can lead to miscalculated exposures, potentially violating workplace air standards.

Purpose of the Study:

• To highlight the evolution and expansion of aerosol inhalability concepts beyond occupational settings.
• To identify potential misrepresentations of exposure in current applications of inhalability sampling.
• To advocate for scientific advancements in understanding and applying inhalability principles.

Main Methods:

• Review and commentary on the historical development and current applications of inhalability conventions.
• Discussion of potential misinterpretations and inaccuracies in exposure assessments.
• Identification of necessary research directions and collaborative approaches.

Main Results:

• The initial focus on workplace air quality has broadened to include general populations, medical patients, and research subjects.
• Certain expanded applications of inhalability sampling may inaccurately reflect actual exposures.
• There is a critical need for scientific progress in the understanding and application of inhalability.

Conclusions:

• Further scientific advances in aerosol inhalability are required.
• Multidisciplinary collaboration involving diverse experts is essential for progress.
• Improved understanding will enhance the accuracy of exposure assessments across various settings.