Related Experiment Video
Updated: Apr 25, 2026

A Decentralized Ex Vivo Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling
Published on: November 28, 2019
Bladder Wash as an Alternative Postmortem Toxicology Specimen: Forensic Pathologists' Perspectives
Luke N Rodda1,2, Kylie E Candela3, Amy P Hart1,4
1Office of the Chief Medical Examiner, San Francisco, CA.
Bladder wash, a novel specimen for postmortem toxicology, is effective for determining cause of death. Forensic pathologists
Area of Science:
- Forensic toxicology
- Postmortem investigations
Background:
- Bladder wash offers a potential alternative specimen for toxicological analysis when other samples are compromised.
- Current use of bladder wash in postmortem investigations is not standardized.
Purpose of the Study:
- To evaluate forensic pathologists' perceptions of bladder wash utility before and after exposure to toxicological data.
- To gauge the potential for standardizing bladder wash collection in forensic investigations.
Main Methods:
- An online survey was distributed to forensic pathologists.
- Responses were analyzed to identify shifts in opinion regarding bladder wash samples.
Main Results:
- Most pathologists acknowledged the benefits of bladder wash for toxicological analysis.
- A notable shift in perspective occurred after participants reviewed supporting data.
- Bladder wash was recognized as valuable for determining cause and manner of death.
Conclusions:
- Bladder wash is a valuable and accessible specimen for postmortem toxicological analysis.
- Standardizing bladder wash collection can provide crucial data when other specimens are unavailable.
- Further adoption of bladder wash analysis can enhance forensic investigations.
More Related Videos
09:50A Single Cell Dissociation Approach for Molecular Analysis of Urinary Bladder in the Mouse Following Spinal Cord Injury
Published on: June 17, 2020
08:53Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
Published on: December 4, 2020
Related Concept Videos
Prevention of Further Absorption of Poison
Enhanced Elimination of Poison
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
Pharmaceutical Poisoning: Treatment Strategies
Urine Studies I: Urinalysis
Imaging Studies VI: Voiding Cystourethrography and Cystography