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Updated: Jul 23, 2026

A Modified Method for Heterotopic Mouse Heart Transplantion
Published on: June 23, 2014
"First-in-human" totally robotic orthotopic heart transplant
Feras H Khaliel1, Muhammad I Haq1, Ahmed K Alsulbud1
1Adult Cardiac Surgery, Heart Centre, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.
Importance:
Traditionally, heart transplantation surgery requires a median sternotomy due to the perceived complexity of a large organ replacement. Whether an alternative minimally invasive approach to perform a successful heart transplant can be accomplished remains uncertain.
Objective:
To develop a safe and effective technique for totally robotic heart transplantation.
Design:
Using a multidisciplinary team, technical timed training using the robot-assisted approach was accomplished on multiple cadavers. Importantly, practice to limit the donor organ ischemic time to ensure patient safety was deemed essential, and once readiness was achieved, an in-vivo operation was undertaken.
Setting:
Academic cardiac surgical unit of King Faisal Specialist Hospital and Research Centre, Riyadh (Saudi Arabia).
Participant:
A 16-year-old boy with refractory biventricular heart failure caused by a nonischemic dilated cardiomyopathy MAIN OUTCOME: A successful totally robotic heart transplant, with a short ischemic time, mechanical ventilation <24 hours, rapid patient mobilization, and reduced postoperative pain and hospital duration of stay.
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