Pharmacists' Intervention in Inappropriate Aspirin Prescribing in a Geriatric Primary Care Clinic

Paige Tulcewicz1, Kimberly Atkinson1, Andrea Koff1

  • 1HCA Florida North Florida Hospital, Outpatient Pharmacy, Gainesville, Florida.

The Senior Care Pharmacist
|February 27, 2025
PubMed

Insights

Pharmacists successfully recommended discontinuing inappropriate aspirin use for primary prevention in older adults. This intervention showed a 75% acceptance rate, improving medication appropriateness in geriatric care.

Area of Science:

  • Geriatric Medicine
  • Cardiovascular Disease Prevention
  • Pharmacist Intervention

Background:

  • Aspirin's role in primary prevention of atherosclerotic cardiovascular disease (ASCVD) is controversial due to lack of improved outcomes and increased bleeding risk.
  • Despite evidence, many older adults continue aspirin for primary prevention, highlighting a gap in guideline adherence.
  • Identifying and addressing inappropriate aspirin prescriptions is crucial for patient safety in geriatric populations.

Purpose of the Study:

  • To evaluate the impact of pharmacist-led interventions on discontinuing inappropriate aspirin prescriptions for primary prevention.
  • To assess the effectiveness of pharmacist recommendations in a geriatric primary care setting.

Main Methods:

  • Retrospective review of patients prescribed aspirin in a geriatric primary care clinic.
  • Pharmacists identified aspirin indications, recommending discontinuation for primary prevention cases.
  • Documented acceptance and decline rates of pharmacist recommendations.

Main Results:

  • Out of 528 patients, 122 (48%) were taking aspirin for primary prevention.
  • Pharmacists recommended discontinuation for 122 patients, with 91 recommendations accepted (75% acceptance rate).
  • A significant proportion of patients were inappropriately prescribed aspirin for primary ASCVD prevention.

Conclusions:

  • Pharmacist review is effective in identifying and discontinuing inappropriately prescribed aspirin for primary ASCVD prevention in older adults.
  • Routine assessment of aspirin appropriateness is necessary to align medication use with current evidence and guidelines.
  • This intervention demonstrates the value of pharmacists in optimizing medication management and improving patient outcomes in geriatric care.

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