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Pharmacists' Intervention in Inappropriate Aspirin Prescribing in a Geriatric Primary Care Clinic
Paige Tulcewicz1, Kimberly Atkinson1, Andrea Koff1
1HCA Florida North Florida Hospital, Outpatient Pharmacy, Gainesville, Florida.
Insights
Pharmacists successfully recommended discontinuing inappropriate aspirin use for primary prevention in older adults. This intervention showed a 75% acceptance rate, improving medication appropriateness in geriatric care.
Area of Science:
- Geriatric Medicine
- Cardiovascular Disease Prevention
- Pharmacist Intervention
Background:
- Aspirin's role in primary prevention of atherosclerotic cardiovascular disease (ASCVD) is controversial due to lack of improved outcomes and increased bleeding risk.
- Despite evidence, many older adults continue aspirin for primary prevention, highlighting a gap in guideline adherence.
- Identifying and addressing inappropriate aspirin prescriptions is crucial for patient safety in geriatric populations.
Purpose of the Study:
- To evaluate the impact of pharmacist-led interventions on discontinuing inappropriate aspirin prescriptions for primary prevention.
- To assess the effectiveness of pharmacist recommendations in a geriatric primary care setting.
Main Methods:
- Retrospective review of patients prescribed aspirin in a geriatric primary care clinic.
- Pharmacists identified aspirin indications, recommending discontinuation for primary prevention cases.
- Documented acceptance and decline rates of pharmacist recommendations.
Main Results:
- Out of 528 patients, 122 (48%) were taking aspirin for primary prevention.
- Pharmacists recommended discontinuation for 122 patients, with 91 recommendations accepted (75% acceptance rate).
- A significant proportion of patients were inappropriately prescribed aspirin for primary ASCVD prevention.
Conclusions:
- Pharmacist review is effective in identifying and discontinuing inappropriately prescribed aspirin for primary ASCVD prevention in older adults.
- Routine assessment of aspirin appropriateness is necessary to align medication use with current evidence and guidelines.
- This intervention demonstrates the value of pharmacists in optimizing medication management and improving patient outcomes in geriatric care.
Abstract:
Background: In recent years, aspirin use has been controversial for primary prevention of atherosclerotic cardiovascular disease (ASCVD) events. Numerous clinical trials have proven that aspirin does not improve outcomes and increases major bleeding rates. Despite clinical trial data and guideline recommendations, there remains a large number of older adults taking aspirin for primary prevention. Objective: Describe the impact that pharmacists had on the discontinuation of inappropriately prescribed aspirin in a geriatric primary care clinic. Methods: This is a retrospective review of patients taking aspirin. A report was generated for all patients with aspirin on their medication list. The pharmacist determined the indication for aspirin. If patients were taking aspirin for primary prevention, the pharmacist recommended aspirin be discontinued. Results: A total of 528 patients were included in this study. There were 321 (61%) females and 207 (39%) males. After analyzing aspirin indication, 122 (48%) were taking aspirin for primary prevention, 273 (52%) were taking aspirin for secondary prevention, and 133 (52%) were taking aspirin for another indication. The recommendation to discontinue aspirin was accepted 91 times and declined 30 times, yielding a 75% acceptance rate. Conclusion: Aspirin has several appropriate indications for use; however, previous studies have shown that risk outweighs benefit when used for primary prevention of ASCVD events in the geriatric population. When aspirin is on a patient's medication list, it should be assessed routinely for appropriateness. This retrospective review by pharmacists highlights the need for review and discontinuation of aspirin when appropriate.
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