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Related Concept Videos

Antiasthma Drugs: Leukotriene Modifiers01:19

Antiasthma Drugs: Leukotriene Modifiers

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Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
Leukotriene modifiers work through two distinct mechanisms:
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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
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Hypersensitivities01:30

Hypersensitivities

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Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
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Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
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Related Experiment Video

Updated: May 25, 2025

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
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Atopic Dermatitis in Adults: Focus on Topical Therapy.

Leisa L Marshall1

  • 1Mercer University College of Pharmacy, Atlanta, Georgia.

The Senior Care Pharmacist
|February 27, 2025
PubMed
Summary

Topical therapies, including moisturizers and anti-inflammatory agents, effectively manage adult atopic dermatitis. Pharmacists play a key role in educating patients on treatment benefits and risks.

Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Atopic dermatitis is a prevalent, chronic inflammatory skin condition affecting adults.
  • It is characterized by relapsing-remitting disease activity.
  • While not curable, symptoms can be managed effectively.

Purpose of the Study:

  • To review current topical therapies for adult atopic dermatitis.
  • To outline treatment recommendations and the role of pharmacists in patient care.

Main Methods:

  • A comprehensive literature search was conducted in PubMed, Cochrane Reviews, and Google Scholar.
  • Included studies were published within the last 10 years.
  • Data synthesis involved reviewing guidelines, research articles, and drug information.

Main Results:

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  • Topical therapies are the preferred treatment for adult atopic dermatitis.
  • Moisturizers are foundational, often supplemented by topical anti-inflammatory agents.
  • Approved agents include corticosteroids, calcineurin inhibitors, PDE4 inhibitors, and JAK inhibitors.

Conclusions:

  • Topical treatments can control atopic dermatitis in most adult patients.
  • Pharmacists are vital in counseling patients on the appropriate use and risks of these therapies.